Erectile Dysfunction Treatment : Viagra, Levitra
and Cialis
There are
only four oral drugs approved by the FDA to treat erectile dysfunction: Viagra, Cialis, Levitra and Staxyn. All work by increasing the flow of blood into
the penis so that when a man is sexually stimulated, he can get an erection.
Viagra, Levitra or Cialis are often
the first treatment tried for erectile dysfunction. For most men who have
trouble keeping an erection firm enough for sex (erectile dysfunction), these
medications work well and cause few side effects.
Sildenafil (Viagra), vardenafil (Levitra) and tadalafil (Cialis) are all
medications that reverse erectile dysfunction by increasing nitric oxide, a
chemical naturally produced by your body. Nitric oxide opens and relaxes blood
vessels in the penis, helping you get and keep an erection. These erectiledysfunction medications don't increase your sex drive, though, and cause
erections only when you are sexually stimulated. Viagra, Levitra and Cialis — Comparison
Although they work in similar ways, each of these medications has a slightly different chemical makeup. These minor differences affect the way each medication works, such as how quickly it takes effect and wears off, and the potential side effects.
Viagra
(Sildenafil)
|
Cialis
(Tadalafil)
|
Levitra
(vardenafil)
|
|
Manufacturer
|
Pfizer
(FDA
approved March 27,1998)
|
LillyIcos
(FDA
approved November 21,2003)
|
Bayer
(FDA
approved April 15,2003)
|
How
to take it
|
Without
food, no more than once a day
|
With
or without food, no more than once a day
|
Without
food, no more than once a day
|
When
to take it
|
60
minutes or longer before sex
|
30
minutes or longer before sex
|
15
- 20 minutes or longer before sex
|
Effectiveness
|
Up
to 5 hours
|
Up
to 36 hours
|
Up
to 6 hours
|
Side effects
Most men who take Viagra, Levitra
and Cialis aren't bothered by side effects. When side effects do occur, they
can include:
- Headache
- Flushing
- Indigestion
- Stuffy or runny nose
- Back pain and muscle aches (with Levitra)
- Temporary vision changes, including "blue vision" (with Viagra)
In a small number of cases, men
taking Viagra, Levitra or Cialis have reported more serious side effects:
- Hearing loss or vision loss. Some men have had sudden loss of hearing or loss of vision after taking one of these medications. However, it isn't clear whether vision or hearing loss was directly caused by taking the medication or by a pre-existing condition. If you're taking one of these medications for erectile dysfunction and have sudden loss of hearing or vision, seek medical help right away.
- An erection that doesn't go away on its own. Called priapism, this rare condition can be painful and requires medical treatment to avoid damage to your penis. If you have an erection that lasts more than four hours, seek medical attention.
What Precautions Should I Take Before Taking One of These Drugs?
There are certain situations in
which these drugs may not be safe to take. Before taking them, tell your GP:
- If you are allergic to any drugs, including Viagra or other ED medications.
- About any prescription or non-prescription medications you are currently taking, including herbal and dietary supplements.
- If you are scheduled for surgery, including dental surgery.
- If you take a long-acting nitrate to treat chest pain. The combination of Cialis, Levitra or Viagra with these drugs can cause dangerously low blood pressure. Like Viagra, Levitra and Cialis, nitrate dilate blood vessels. The combined effects can cause dangerous low blood pressure and loss of consciousness.
Medications that
contain nitrates include:
ü Nitroglycerin
(Nitro-Bid, Minitran, others)
ü Isosorbide
(Dilatrate-SR, Isordil, Monoket, others)
ü Illegal drugs
such as amyl nitrite or "poppers"
- If you take alpha-blockers for blood pressure or prostate problems. The combination of Cialis, Levitra or Viagra with these drugs can also cause dangerously low blood pressure.
· In addition,
always follow the directions on your prescription label carefully and ask your GP
or pharmacist to explain any part that you do not understand. Take these
drugs exactly as directed. Do not take more or less or take it more often than
prescribed by your GP. Do not take these drugs more than once a day.
· Tell your GP about any medications you're
taking. A number of other drugs can also interact with Viagra, Levitra or
Cialis, which including:
ü Antibiotics
ü Anti-seizure
medications
ü Blood thinners
ü Anti-arrhythmic
heart medications
If One of These Drugs Isn't Effective for ErectileDysfunction, Can I Try Another?
Yes, but because these drugs work the same way, it's
unlikely that you'll have success with one if you've failed to achieve an
adequate erection with another.
Who Should Not Take Cialis, Levitra or Viagra?
If you have suffered from a heart attack, stroke or
life threatening arrhythmia (irregular heart rate) within the last
6 months you should discuss other options with your GP. It is also advised to
avoid these drugs if you have uncontrolled high or low blood pressure or if you
experience chest pain with sex.
Other medications
- Psychological counselling. If your erectile dysfunction is caused by stress, anxiety or depression, your GP may suggest that you, or you and your partner, visit a psychologist or counselor. Even if it is caused by something physical, erectile dysfunction can create stress and relationship tension.
- Testosterone replacement. Some men have erectile dysfunction caused by low levels of the hormone testosterone, and may need testosterone replacement therapy.
- Alprostadil self-injection. With this method, you use a fine needle to inject alprostadil (Alprostadil, Caverject Impulse, Edex) into the base or side of your penis. In some cases, medications generally used for other conditions are used for penile injections on their own or in combination. Examples include papaverine, alprostadil and phentolamine. Each injection generally produces an erection in five to 20 minutes that lasts about an hour. Because the needle used is very fine, pain from the injection site is usually minor. Side effects can include bleeding from the injection, prolonged erection and formation of fibrous tissue at the injection site.
- Penis pumps. A penis pump (vacuum constriction device) is a hollow tube with a hand-powered or battery-powered pump. The tube is placed over your penis, and then the pump is used to suck out the air inside the tube. This creates a vacuum that pulls blood into your penis. Once you get an erection, you slip a tension ring around the base of your penis to hold in the blood and keep it firm. You then remove the vacuum device. The erection typically lasts long enough for a couple to have sex. You remove the tension ring after intercourse.
- Penile implants. This treatment involves surgically placing devices into the two sides of the penis. These implants consist of either inflatable or semi-rigid rods made from silicone or polyurethane. The inflatable devices allow you to control when and how long you have an erection. The semi-rigid rods keep the penis firm but bendable. This treatment can be expensive and is usually not recommended until other methods have been tried first. As with any surgery, there is a risk of complications such as infection.
- Blood vessel surgery. In rare cases, a leaking blood vessel can cause erectile dysfunction and surgery is necessary to repair it.
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